Organic Nanoparticles ONPs

The synthesis, functionalization and biomedical applications of ONPs is a broad field. In this section we give one approach to the subject, illustrated with some examples. 

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To build a nanoparticle that is made entirely of the functional organic molecule, like some of the fluorescent ONPs from Wang Lun s group [67, 68]. 

To build a nanoparticle in a core-shell strategy. The cores are synthesized first and then the functional molecules are added as a shell by simple adhesion (physical adsorption in an insolubilization strategy). Examples are given in the literature [71, 72]. Organic molecules forming the core of an ONP usually include functional groups to which other molecules are added, such as peptides/ proteins and nucleic acids. 

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