Organic acids, electrophoretic mobility prediction

CE has been applied in the analysis of organic acids (27). The key parameter in these analyses is electrophoretic mobility, which depends on both molecular structure and separation conditions. Therefore, developing chemometrical models to predict the mobilities of ions will relieve analysts of a large number of costly and time-consuming experiments. Two principal methods based on the quantitative relationship between molecular structures and elec-... 

For the sake of comparison, the results of the mechanistic model are also given in Table 14.2. To assess the robustness of the models, a 10-fold cross-validation method was used on all data sets (29). The consistency of the results of cross validation for all groups proved the stability and robustness of the models. Figure 14.6 demonstrates the plot of the CART-ANFIS calculated values for the acid mobilities against the experimental values. The high value of R = 0.970 for this plot indicates that the CART-ANFIS model can be considered as a powerful tool for the prediction of the electrophoretic mobihty of organic and sulfonic... 

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