Optical tweezer techniques bead trapping

Raman probes. SERS can then be performed on optically induced aggregates of the trapped particles. Alternatively, metal nanoparticles can also be attached on micron-sized dielectric beads, which are much easier to trap. Raman probes can be adsorbed on the surface of the metal nanoparticles. In addition, combined with other techniques, such as microfluidics, the applicability of optical tweezers for SERS can be even more expanded. 

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