Oogenesis materials

While not yet conclusive, studies on the gray crescent described above may provide yet another example of substances accumulated within the GV during oogenesis which become effective only after dispersal into the cytoplasm. It would be most significant if these or other nuclear products could be related to the cytoplasmic localizations referred to earlier. Whether any of the examples yet discussed falls into this category remains to be seen and will depend to a large- extent on continued attempts to identify the nature of the active materials and their mode of action. This alone requires continued interest in the period of maturation. However, it is possible that the various factors described above are involved in more generalized metabolic functions which, while necessary to normal development, are not directly involved in the differentiation of specific cell types. 

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