One-Pot Multicomponent Synthesis of p-Acetamido Ketones

B. Das, K. Reddy, R. Ramu, P. Thirupathi, B. Ravikanth, Synlett 2006, 2006, 1756-1758. Iodine as an efficient catalyst for one-pot multicomponent synthesis of P-acetamido ketones. 

BiCla in situ generated from the procatalyst BiOCl was proved to be very efficient in the catalyzed one-pot multicomponent synthesis of P-acetamido ketones from a variety of aromatic aldehydes, enolizable ketones, acetyl chloride, and aceto or benzonitrile (Equation 13) [33cj. 

---