Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Oligosaccharide synthesis cleavage method

Cleavage Methods for Solid-Phase Oligosaccharide Synthesis... [Pg.42]

The fj-nitrobenzyl and p-nitrobenzyl ethers can be prepared and cleaved by many of the methods described for benzyl ethers. In addition, the o-nitrobenzyl ether can be cleaved by irradiation (320 nm, 10 min, quant, yield of carbohydrate 280 nm, 95% yield of nucleotide ). This is one of the most important methods for cleavage of this ether. These ethers can also be cleaved oxidatively (DDQ or electrolysis) after reduction to the aniline derivative." Clean reduction to the aniline is accomplished with Zn(Cu) (acetylacetone, rt, >93% yield).Hydrogenolysis is also an effective means for cleavage. A polymeric version of the o-nitrobenzyl ether has been prepared for oligosaccharide synthesis that is also conveniently cleaved by photolysis. An unusual selective deprotection of a bis-o-nitrobenzyl ether has been observed. The photochemical reaction of o-nitrobenzyl derivatives has been reviewed. ... [Pg.135]


See other pages where Oligosaccharide synthesis cleavage method is mentioned: [Pg.72]    [Pg.10]    [Pg.23]    [Pg.206]    [Pg.208]    [Pg.199]    [Pg.101]    [Pg.43]    [Pg.25]    [Pg.83]    [Pg.1261]    [Pg.1269]    [Pg.1273]    [Pg.27]    [Pg.63]    [Pg.68]    [Pg.209]    [Pg.137]    [Pg.115]    [Pg.512]    [Pg.523]    [Pg.353]    [Pg.528]    [Pg.113]    [Pg.137]    [Pg.244]    [Pg.486]    [Pg.704]    [Pg.229]    [Pg.44]    [Pg.191]    [Pg.285]    [Pg.170]    [Pg.44]    [Pg.622]    [Pg.623]    [Pg.187]    [Pg.615]    [Pg.1251]    [Pg.1258]    [Pg.285]    [Pg.19]    [Pg.602]    [Pg.605]    [Pg.69]    [Pg.671]    [Pg.585]    [Pg.659]    [Pg.222]   
See also in sourсe #XX -- [ Pg.42 ]




SEARCH



Cleavage methods

Oligosaccharide methods

© 2024 chempedia.info