Oligomer backbone

Within this chapter, a review is given on the classical approaches to introduce polymerizable endgroups into the (imide) oligomer backbone. The... 

Oligomer backbone structure -OCH2CH2OOC-, -OOT-CH2OOC-, -OCH2, or CH3... 

We have chosen to use hydroxy vinyl ethers (CH2—CH-O-R-OH) as intermediates in the synthesis of vinyl ether functionalized oligomers. Hydroxy vinyl ethers are easily obtained as by-products of the synthesis of dlvlnyl ether monomers (Equation 1). The hydroxy group may be reacted to form a link to the oligomer backbone while the vinyl ether moiety remains free to be polymerized in a radiation induced reaction at a later time. 

MOs (Figure 23.2). Owing to the significant structural differences between these novel oligomer backbones and natural oligonucleotides, they do not activate RNase H-mediated degradation with the exception of FANA, but instead, block translation through steric hindrance [1]. 

Over the past decade, conjugated polymers (CPs) have been widely implemented in amperometric biosensors [278-280]. The integration of biomolecules to the backbone of CPs is a difficult process and a key challenge towards the design and preparation of biosensory materials. The functionalization of CPs can be achieved in three different ways (1) the attachment of biomolecules to the oligomer backbone prior to their polymerization, (2) the attachment of biomolecules to the polymer backbone during the polymerization processes and (3) the attachment of biomolecules by covalent linkages to reactive CP films. In the last two cases, however, it is difficult to estimate the attached biofunctionality to the CP backbones. 

The high antibiotic activities of these relatively simple facially amphiphilic oligomers prompted researchers to further explore facial amphiphiles with rigidified oligomer backbones as possible antibiotics. For instance, a similar system based on urea-linked oligomers was investigated by Tew et al. (Figure 16c). These compounds show... 

The spectrum exhibits a broad distribution with maximum intensity at 2950 mass units (m/z). The distance between the peaks was 160 which is one unit of a completely methylated xylose. Complete methylation of the sample was also confrrmed by FT-IR (28). The maximum mass peak therefore corresponded to one 4-Omethylglucuronic (40MeGlcA) residue linked to the xylo-oligomer backbone with a DP of 17. Two series of oligosaccharides were found with... 

PIA bands appear in the near IR at around < 0.8 eV which shift to the red on increasing the chain length. The near IR absorption at around 0.8 eV and the shoulder at 1.5 eV (especially visible in six membered and seven membered oligothiophene 6T and 7T, Figure 8.35) are the charged photoexcitations on the oligomer backbone. 

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