Olefination of Carbonyl Compounds by Zinc and Chromium Reagents

Olefination of Carbonyl Compounds by Zinc and Chromium Reagents 

Such compounds have two C-M bonds on the same carbon atom [3]. The first C-M bond serves to promote nudeophilic attack on the carbonyl compound, and the second fadlitates the subsequent j8-elimination of a metal oxide. As a result, an 

These organometallic reagents, however, are also associated with some problems. Compared to the Wittig reagent, they are sometimes difficult to handle because of instability, and in some cases they are prohibitively expensive. In order to obtain a desired product, these practical problems can often be ignored, but some stable and easily available gem-dimetal species have recently been developed that may make such considerations unnecessary. In this chapter, gem-dimetal reagents incorporating zinc and chromium are discussed. 

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Matsubara, S. Oshima, K. Olefination of Carbonyl Compounds by Zinc and Chromium Reagents. In Modem Carbonyl Olefination-, Takeda, T., Ed. Wiley-VCH Weinheim, 2004 pp 200—222. 

I 5 Olefination of Carbonyl Compounds by Zinc and Chromium Reagents 5.4.1... 

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