Of ascocorynin

Recently a new general synthesis of terphenylquinones has been developed which makes use of the methoxide catalysed rearrangement of grevillins (Scheme 5) 462). Because the starting materials (20) are easily prepared from pyrandiones of type (8) (Scheme 2) this method offers an efficient and versatile route to unsymmetrically substituted and specifically carbon-labelled terphenylquinones 366). Besides poly-poric acid (11), ascocorynin (12), and leucomelone (19) a number of analogues containing heterocyclic or styryl residues have been prepared 462). The enolate (21) involved in this transformation is similar to... 

Atromentin (13) is a key intermediate for further conversions, e.g. to more highly hydroxylated terphenylquinones and to pulvinic acids (see Section 2.1.3). Whereas polyporic acid (11) and ascocorynin (12) have not been observed as co-metabolites of more highly hydroxylated terphenylquinones, atromentin or its derivatives often co-occur with cycloleucomelone (14) (e.g. in Paxillus and Anthracophyllum) and with thelephoric acid (16) (e.g. in Hydnellum). In cultures of Omphalotus subilludens ( = Clitocybe subilludens) the relative proportion of atromentin to thelephoric acid decreases with ageing, which provides a strong indication that thelephoric acid is derived from atromentin (637). 

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