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Ocular acetylcholinesterase

An optimal ocular prodrug should be hydrolyzed by several esterases in order to minimize the effect of individual esterase levels on enzymatic transformation of ocular prodrugs.75 In rabbits (the typical model used during initial development of ophthalmic drugs), acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) are considered critical in the... [Pg.91]

See other pages where Ocular acetylcholinesterase is mentioned: [Pg.237]    [Pg.237]    [Pg.33]    [Pg.80]    [Pg.239]    [Pg.103]    [Pg.130]    [Pg.132]    [Pg.135]    [Pg.907]    [Pg.90]    [Pg.13]    [Pg.238]    [Pg.124]    [Pg.97]    [Pg.277]    [Pg.536]   
See also in sourсe #XX -- [ Pg.237 ]



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