Octopus-type cyclophane

Cyclophanes are cyclic hosts made by Unking aromatic rings. Several examples of cyclophanes are depicted in Fig. 2.21. While the cyclophane in (a) is a simple two-dimensional cyclophane, the cyclophane in (b) has four alkyl chains attached. Using a similar molecular design process, a cyclophane with eight alkyl chains can be synthesized and is called an octopus-type cyclophane. The alkyl chains self-assemble in an aqueous phase and form a three-dimensional cavity. Cyclophanes with rigid steroidal walls are called steroid... 

Fig. 3A-C. Space-filling models of artificial receptors, each being capable of providing a large hydrophobic cavity A octopus cyclophane 4 B steroid cyclophane 6 C cage-type cyclophane 8...

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