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Octanol-impregnated filters

Cools and Janssen [545] studied the effect of background salt on the permeability of warfarin through octanol-impregnated membranes (Millipore ultrafiltration filters, VSWP, 0.025-pm pores). At a pH where warfarin was in its ionized form, it was found that increasing background salt increased permeability (Fig. 7.7). This... [Pg.124]

Figure 7.8 Permeation of drugs through oil-soaked microfilters comparisons to Caco-2 permeabilities (dashed curves) [546] (a) oil-free (untreated hydrophilic) filters (b) unstirred water layer permeability versus log MW (c) octanol-soaked (impregnated) filters (d) isopropylmyristate-soaked filters. Figure 7.8 Permeation of drugs through oil-soaked microfilters comparisons to Caco-2 permeabilities (dashed curves) [546] (a) oil-free (untreated hydrophilic) filters (b) unstirred water layer permeability versus log MW (c) octanol-soaked (impregnated) filters (d) isopropylmyristate-soaked filters.
See other pages where Octanol-impregnated filters is mentioned: [Pg.144]    [Pg.144]    [Pg.248]    [Pg.48]    [Pg.19]    [Pg.126]    [Pg.48]   
See also in sourсe #XX -- [ Pg.126 , Pg.127 ]



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2 Octanol

Impregnate

Impregnating

Impregnation

Impregnator

Octanols

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