Obesity hypoventilation syndrome

Unlabeled Uses Sleep apnea, congenital central hypoventilation syndrome, obesity-hypoventilation syndrome, postanesthetic respiratory depression, shivering... 

Mixed ventilatory disorders Bronchiectasis Sequelae of tuberculosis Nonpulmonary diseases Dysfunction of respiratory centers Primary alveolar hypoventilation Obesity hypoventilation syndrome Depressant drugs Myxoedema Lesion of brainstem Neuromuscular diseases Poliomyelitis... 

Teichtahl H. The obesity-hypoventilation syndrome revisited. Chest 2001 120 336-339. 

Obesity-hypoventilation syndrome Stable neuromuscular disorders Old poliomyelitis Myopathies... 

Figure 10 Encore Pro software (Respironics) report from an obesity hypoventilation syndrome patient using bi-level with volume security. Abbrex iation AVAPS, average volume-assured pressure support.

Figure 1 Patients presenting with OHS. Abbreviation OHS, obesity hypoventilation syndrome.

Figure 2 Life expectancy of patients with OHS. (A) Spontaneous life expectancy (38), N = 148 patients. (B) Comparison between OHS and various etiologies of CRF (9). Abbreviations OHS, obesity hypoventilation syndrome CRF, chronic respiratory failure.

Figure 3 Ventilatory polygraphy of a patient with severe OHS IAH = 26 Pao = 9.6 kPa Paco = S 5 kPa (O2 3L/imn) lh/Jviarw OHS, obesity hypoventilation syndrome lAH, intra-abdominal hypertension Paco2, partial pressure of carbon dioxide in arterial blood.

Figure 6 Ventilatory management in OHS and ARF. Abbreviations OHS, obesity hypoventilation syndrome ARF, acute respiratory failure. Source From Ref. 47.

Oison AL, Zwillich C. The obesity hypoventilation syndrome. Am J Med 2005 118 948-956. Phipps PR, Starritt E, Goiinszein RR, et al. Association of serum leptin with hypoventilation in human obesity. Thorax 2002 57 75-76. 

Yee B, Cheung J, Phipps P, et al. Treatment of obesity hypoventilation syndrome and serum leptin. Respiration 2006 73 209-212. 

Pankow W, Hijjeh I, Sehutder F, et al. Influenee of noninvasive positive pressure ventilation on inspiratory musele aetivity in obese subjects. Eur Respir J 1997 10 2847-2852. de Lucas-Ramos P, de Miguel-Diez J, Santaeruz-Siminiani A, et al. Benefits at 1 year of nocturnal intermittent positive pressure ventilation in patients with obesity-hypoventilation syndrome. Respir Med 2004 98 %l-967. 

Jokic R, Zintel T, Sridhar G, et al. Ventilatory responses to hyperctqtnia and hypoxia in relatives of patients with the obesity hypoventilation syndrome. Thorax 2000 55 940-945. 

Banneijee D, Yee BJ, Piper AJ, et al. Obesity hypoventilation syndrome hypoxemia during CPAP. Chest, 2007 131 1678-1684. 

Masa JF, Celli BR, Riesco JA, et al. The obesity hypoventilation syndrome can be treated with noninvasive mechanical ventilation. Chest 2001 119 1102-1107. 

Cuvelier A, Muir JF. Obesity hypoventilation syndrome new insights in the Pickwick papers [editorial]. Chest 2007 131 7-8. 

Figure 3 Percentage of users in each disease category by country. The symbol represents lung/ airways (COPD, cystic fibrosis, bronchiectasis, pulmonary fibrosis, and pediatric diseases) , chest wall deformities (kyphoscoliosis, old TB, OHS, surgical resection) and , neuromuscular disorders (muscular dystrophy, motor neuron disease, post-polio kyphoscoliosis, central hypoventilation, spinal cord damage, and phrenic nerve palsy). Abbreviations COPD, chronic obstructive pulmonary disease TB, tuberculosis OHS, obesity hypoventilation syndrome. Source From Ref. 15.

---