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O-Tolylmagnesium chloride

Certain pyridines react with Grignard reagents in the 1,4-manner when substituted by electron-withdrawing groups such as a carboxamide <2000J(P1)4245, 2005JOC2000>. The intermediate dihydropyridine can conveniently be oxidized to the pyridine structure. An example of this is seen in the reaction of 6-chloronicotinic acid derivative 125 with an excess of o-tolylmagnesium chloride, followed by oxidation with 2,3-dichloro-5,6-dicyano-l,4-benzoquinone... [Pg.64]

See other pages where O-Tolylmagnesium chloride is mentioned: [Pg.182] [Pg.183] [Pg.182] [Pg.183] [Pg.86] [Pg.153] [Pg.10] [Pg.182] [Pg.183] [Pg.182] [Pg.183] [Pg.86] [Pg.153] [Pg.10] [Pg.99] [Pg.178] [Pg.115]

See also in sourсe #XX -- [ Pg.9 ]

See also in sourсe #XX -- [ Pg.132 ]

See also in sourсe #XX -- [ Pg.132 ]

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O chloride