O-Acetyl groups in sialic acids

In m.s., partially methylated sialic acids also lead to characteristic fragments that can be used for analysis of natural, or synthetic, O-methylated sialic acids.57,96,139-147 Methyl ether derivatives are obtained in methylation analyses for structural studies of sialyl-sialyl linkages, or in experiments for the localization of O-acetyl groups in sialic acids. For the identification of such Neu derivatives, the 0-(tri-... 

C-N.m.r.-spectroscopic analyses have been successfully made for determination of the position of O-acetyl groups in sialic acids, using the 9-O-acetyl- and 4,9-di-O-acetyl derivatives of Neu-/3-Me methyl ester as model compounds,9 1 or in the sialic acid residues of polysaccharide antigens ofN. meningitidis.166 1... 

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