Nucleotides acids

In the past, general chapters and reviews have been published, related to the characteristics of CL as analytical technique [7-9], mainly in the liquid phase [10-14], and its use as detection mode in flowing streams and immunoassay [15-17]. Two extensive reviews reported on the specific application of CL reactions according to the nature of the analyte (inorganic species, enzymes and nucleotides, acids and amines, carbohydrates, steroids, polycyclic aromatic compounds, and drugs) and covering the literature from 1983 to 1991 [18] and from 1991 to mid-1995 [19]. 

Acid-soluble nucleotides Acid-alcohol precipitant Perchloric acid Uranyl-acetate-trichloracetic acid Uranyl-acetate pH 4 BaC10 + Cellosolve Coprecipitation problems (401) (43) (103) (402) (403, 404) (405)... 

Receptor Nucleotide acid Major Minor Caucasians Americans... 

Nucleotide acid anhydrides represent activated forms of their X component. The X may be transformed to another substance (Table III), may be transferred to an acceptor (Table IV), or X itself may bear a group which is activated, by virtue of its association with the anhydride compound, e.g., acetate in acetyl coenzyme A. All of these anhydrides can fimction naturally in catalytic amounts as coenzymes. 

Some Transformations of the X Component of Nucleotide Acid Anhtdrideh... 

Transfer of X Component OF Nucleotide Acid Anhydrides TO Acceptors... 

The enzymic reactions responsible for anhydride synthesis are reversible, and in some cases such as in DPN S3rnthesis, the equilibrium constant is close to unity (387). There are, however, several mechanisms by which formation of a nucleotide acid anhydride can be encouraged, and its destruction by the reverse reaction prevented. This may be illustrated in the synthesis of adenosine-5 -phosphosulfate (APS) which takes place by a reversible reaction that strongly favors its destruction [Eq. (77)] (334)... 

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