Nucleophilic Reactions of OH Groups

The basic principles governing nucleophilicity, such as the steric effects making primary OH groups more nucleophilic than secondary OH groups, or, in a 

Carbohydrate hydroxyl groups are alkylated in three contexts analysis of polysaccharide sequences, dealt with in Section 4.2.1 protection of OH groups during synthetic transformations, which requires the alkyl residues to be removable and the modification of cheap polysaccharides, such as starch and cellulose, for more desirable properties. 

Production of alkylated celluloses requires material free of other polysaccharides, so dissolving pulps , produced under acid pulping conditions which remove 

Electrophile Substituent Commercial acronym DS Solubility Uses 

CH3CI CH3CH2CI Cell-0-CH2CH3 EC 2.S-2.6 Organic Films, lacquers 

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