Nucleophile of hydrogen

Strukul and coworkers have carried out the catalytic epoxidation of a,/3-unsaturated ketones with H2O2 mediated by a series of platinum diphosphine based complexes, that confirm the ability of the Pt(II) center to increase the nucleophilicity of hydrogen peroxide . Interestingly, this transformation may be accomplished in enantioselective fashion when chiral diphosphines such as those in 53 are used (ee up to 63%). 

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