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Nuclear Receptor Engineering

Nuclear receptor LBDs were engineered to have an amino-terminal polyhistidine fusion tag. Constructs were expressed in E. coli strain BL21 (DE3) using the T7 promoter. PPARa LBD was also expressed as a polyhistidine tagged recombinant in baculovirus infected T. ni. [Pg.458]

Chemical Biology of NHRs and the Potential of Engineered Nuclear Receptors... [Pg.185]

D.J. Mangelsdorf, Engineering novel specificities for ligand-activated transcription in the nuclear hormone receptor RXR, Chem. Biol. 1998, 5, 13-21. [Pg.193]

See other pages where Nuclear Receptor Engineering is mentioned: [Pg.183]    [Pg.183]    [Pg.360]    [Pg.274]    [Pg.127]    [Pg.67]    [Pg.1324]    [Pg.1855]    [Pg.1866]    [Pg.457]    [Pg.465]    [Pg.180]    [Pg.184]    [Pg.307]    [Pg.360]    [Pg.361]    [Pg.123]    [Pg.236]    [Pg.219]    [Pg.102]    [Pg.173]    [Pg.1311]    [Pg.2136]    [Pg.55]    [Pg.917]    [Pg.723]    [Pg.575]    [Pg.729]    [Pg.286]    [Pg.32]    [Pg.537]    [Pg.1300]   
See also in sourсe #XX -- [ Pg.183 ]



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