Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Nuclear-cytoplasmic trafficking

Modulation of Nrf2/ARE Signaling Nuclear-Cytoplasmic Trafficking 415... [Pg.401]

MODULATION OF NRF2/ARE SIGNALING NUCLEAR-CYTOPLASMIC TRAFFICKING... [Pg.415]

Lee S, Neumann M, Stearman R, Stauber R, Pause A, Pavlakis GN, Klausner RD. Transcription-dependent nuclear-cytoplasmic trafficking is required for the function of the von Hippel-Lindau tumor suppressor protein. Mol Cell Biol 1999 19 1486-1497. [Pg.63]

Figure 11.1 The intracellular trafficking pathway of plasmid DNA complexed by poly cationic lipid (lipoplex). Critical steps are indicated by numbers (1) endocytosis, sorting and recycling via vesicular compartments comprising the early (EE) and sorting endosomes (2) entrapment and degradation in the late-endosomes (LE) and lysosomes (3) destabilization of the endo-lysosomal membrane and release into the cytosol, (the precise location of this step is not known) (4) diffusion toward the nuclear pore complex (NPC) and degradation in the cytoplasm, and (5) nuclear translocation across the NPC. Figure 11.1 The intracellular trafficking pathway of plasmid DNA complexed by poly cationic lipid (lipoplex). Critical steps are indicated by numbers (1) endocytosis, sorting and recycling via vesicular compartments comprising the early (EE) and sorting endosomes (2) entrapment and degradation in the late-endosomes (LE) and lysosomes (3) destabilization of the endo-lysosomal membrane and release into the cytosol, (the precise location of this step is not known) (4) diffusion toward the nuclear pore complex (NPC) and degradation in the cytoplasm, and (5) nuclear translocation across the NPC.
Figure 3 Quantifying nuclear trafficking - Experimental ratios of the amount of NF-kB antibody staining in the nucleus as compared to the cytoplasm, for unstimulated and stimulated (10 ng/ml TNF-a) HeLa cells. The Z-factor for the assay was 0.73. The CV was 6.3%... Figure 3 Quantifying nuclear trafficking - Experimental ratios of the amount of NF-kB antibody staining in the nucleus as compared to the cytoplasm, for unstimulated and stimulated (10 ng/ml TNF-a) HeLa cells. The Z-factor for the assay was 0.73. The CV was 6.3%...
The function of SIOOP has never been determined with precision however, it is thought to function in intracellular calcium trafficking, or microtubular assembly, or both. It has a loose physiologic relationship to calmodulin, another calcium flux protein.There are two subunits to SIOOP—alpha and beta—yielding three possible dimeric forms alpha-alpha alpha-beta and beta-beta. Melanocytes synthesize only the hrst of those combinations. Immunoreactivity for SIOOP should be both nuclear and cytoplasmic in order to be regarded as valid. Immunoelectron microscopic studies... [Pg.192]

See other pages where Nuclear-cytoplasmic trafficking is mentioned: [Pg.342]    [Pg.415]    [Pg.416]    [Pg.342]    [Pg.415]    [Pg.416]    [Pg.138]    [Pg.230]    [Pg.268]    [Pg.347]    [Pg.175]    [Pg.55]    [Pg.191]    [Pg.193]    [Pg.198]    [Pg.200]    [Pg.229]    [Pg.212]    [Pg.74]    [Pg.348]    [Pg.350]    [Pg.392]    [Pg.396]    [Pg.397]    [Pg.5127]    [Pg.53]    [Pg.2173]    [Pg.519]    [Pg.264]    [Pg.35]    [Pg.5126]    [Pg.225]    [Pg.551]    [Pg.560]    [Pg.238]    [Pg.402]    [Pg.403]    [Pg.494]    [Pg.3501]    [Pg.294]    [Pg.807]    [Pg.258]    [Pg.165]    [Pg.58]   
See also in sourсe #XX -- [ Pg.415 ]



SEARCH



Cytoplasm

Trafficking

© 2024 chempedia.info