Normal cyanide metabolic pathways

Lang demonstrated that an enzyme which he called rhodanese (thiosulphate cyanide sulphurtransferase, E.C.-2.8.1.1.) accelerates the formation of thiocyanate from cyanide and thiosulphate, liver and kidney homogenates being p2irticularly active [41]. 

In addition to that formed by the detoxication of cyanide, there are other sources of thiocyanate in body fluids, e.g. dietary thiocyanate in green vegetables and milk in Europeans dietary thiocyanate probably accounts for mean plasma concentrations in non-smokers of 5.5 jUmoles/lOO ml. In healthy non-smoking Nigerians, however, dietary sources of thiocyemate are probably negligible, since Brassicae are not represented. 

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