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Nonsteroidal antiinflammatory agents platelet aggregation

An imidazoquinazoline constitutes still another compound that does not fall in the classification of a nonsteroid antiinflammatory agent yet shows good platelet anti aggregating activity. Condensation of benzyl chloride 128 with the ethyl ester of glycine gives alkylated product... [Pg.244]

Because of the resonance stabilization possible in its deprotonated form, the 5-tetrazolyl moiety is actually nearly as acidic (pKa ca. 6) as many carboxylic acids. This has led to its inclusion in many drug series as a carboxyl surrogate. Apparently related in concept to indomethacin (26a), intrazole (26) is a nonsteroidal antiinflammatory agent which also inhibits platelet aggregation, and therefore is of potential value in keeping the contents of the... [Pg.345]


See other pages where Nonsteroidal antiinflammatory agents platelet aggregation is mentioned: [Pg.228]    [Pg.1293]    [Pg.374]    [Pg.203]    [Pg.1277]    [Pg.194]    [Pg.194]    [Pg.226]   
See also in sourсe #XX -- [ Pg.505 ]




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Agent aggregation

Antiinflammatories

Antiinflammatory

Antiinflammatory agents

Nonsteroid antiinflammatory agents

Nonsteroidal antiinflammatory

Nonsteroidal antiinflammatory agents

Platelet aggregating agents

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