Noninvasive positive-pressure ventilation NPPV

Noninvasive positive-pressure ventilation (NPPV) provides ventilatory support with oxygen and pressurized airflow using a face or nasal mask with a tight seal but without endotracheal intubation. In patients with acute respiratory failure due to COPD exacerbations, NPPV was associated with lower mortality, lower intubation rates, shorter hospital stays, and greater improvements in serum pH in 1 hour compared with usual care. Use of NPPV reduces the complications that often arise with invasive mechanical ventilation. NPPV is not appropriate for patients with altered mental status, severe acidosis, respiratory arrest, or cardiovascular instability. 

Ohi M, Akashiba T, Ishikawa Y, et al. Guideline for Noninvasive Positive Pressure Ventilation (NPPV) [in Japanese]. Edited by the Noninvasive Positive Pressure Ventilation (NPPV) Guidelines Development Committee of The Japanese Respiratory Society. Tokyo, Nankodo. 

Abbreviation. NPPV, noninvasive positive pressure ventilation. 

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