Non-covalent Encapsulation - Dendritic Box

The encapsulation of small guest molecules was achieved by constructing the dendrimer shell in the presence of the guest molecules followed by extensive dialysis to remove free guest molecules in solution [11]. A variety of probe molecules were applied, including Rose Bengal, 7,7,8,8,-tetracyano-quino-dimethane (TCNQ) and 3-carboxy-PROXYL. UV-Vis, fluorescence and EPR 

Pyrene was used as a fluorescent probe to sense various hydrophobic sites in the microheterogeneous architecture offered by PAMAM dendrimers, possessing an ammonia core and sodium carboxylated surface (Gn.5, n = 0-9) [17]. The IJIi ratio of pyrene in the presence of low generations (G0.5-G3.5) remained very similar to those in pure water. In the presence of higher generation dendrimers, however, pyrene sensed a more hydrophobic outer surface which was presum- 

---