Non-competitive interaction between

Ayesh S, Shao Y-M, Stein WD (1996) Co-operative, competitive and non-competitive interactions between modulators of P-glycoprotein. Biochim Biophys Acta 1316, 8-18. 

Non-competitive interaction between calcium and the calcium channel blocking drugs 258... 

NON-COMPETITIVE INTERACTION BETWEEN CALCIUM AND THE CALCIUM CHANNEL BLOCKING DRUGS... 

Competitive and Non-Competitive Interactions between Modulators of P-Glycoprotein. 

The interesting polymer-solubility behaviour led us to compare this phenomenon with classical LCST effects. In our case, because of the reversible complex formation between the polymer P20 and CD, the optical effect is based on supramolecular interactions. This means that the discovered pseudo-LCST behaviour is a result of non-covalent interactions between the CD host and polymer guest. Furthermore, in this system competitive inhibition or control of the LCST is possible by addition of other suitable guest molecules of low molecular weight, for example, potassium 1-adamantylcarboxylate. CD complexes these molecules preferably and the polymer precipitates. This special effect cannot be observed in regular LCST systems. 

Systematie study of the cosolvency phenomenon has been practically limited to polymethylmethacrylate " and polystyrene. " The cosolvency is usually explained in terms of the molecular characteristics of the system, specially in terms of molecular interactions. In the powerful cosolvents of PMMA described in the literature one of the liquid components is always either acetonitrile or an alcohol. These are non-random liquids with a certain degree of order in their structure. Two important characteristics seem to be present in these polymer cosolvent systems die liquid order structure and the tendency of the polymer towards association. The roles of fliese two factors were considered to interpret solvation of PMMA chains in cosolvent systems. " The mechanisms of cosolvent action have been discussed in terms of the competitive interactions between liquid components and one liquid component and the polymer. " The best example is tire case of acetonitrile and a second liquid having a high proportion of methylene units in its molecule, the unfavorable nitrile-methylene interactions between acetonitrile and PMMA favor... 

In some cases, e.g., the Hg/NaF q interface, Q is charge dependent but concentration independent. Then it is said that there is no specific ionic adsorption. In order to interpret the charge dependence of Q a standard explanation consists in assuming that Q is related to the existence of a solvent monolayer in contact with the wall [16]. From a theoretical point of view this monolayer is postulated as a subsystem coupled with the metal and the solution via electrostatic and non-electrostatic interactions. The specific shape of Q versus a results from the competition between these interactions and the interactions between solvent molecules in the mono-layer. This description of the electrical double layer has been revisited by... 

Skovsgaard, T., Stein, W. D., Competitive, non-competitive and cooperative interactions between substrates of P-glycoprotein as measured by its ATPase activity, Biochim. Biophys. Acta 1997, 3363, 169-176. 

Thus the presence of steps for the interaction between various intermediates in the detailed mechanisms is only a necessary condition for the multiplicity of steady states in catalytic reactions. A qualitative analysis of the dynamic system (5) for mechanism (4) showed that the existence of several stable steady states with a non-zero reaction rate needs the following additional conditions (a) the stoichiometric coefficients of intermediates must fit definite relationships ensuring the kinetic competition of these substances [violation of conditions (6)] (b) the system parameters must satisfy definite inequalities. 

Fundamental studies on the adsorption of supercritical fluids at the gas-solid interface are rarely cited in the supercritical fluid extraction literature. This is most unfortunate since equilibrium shifts induced by gas phase non-ideality in multiphase systems can rarely be totally attributed to solute solubility in the supercritical fluid phase. The partitioning of an adsorbed specie between the interface and gaseous phase can be governed by a complex array of molecular interactions which depend on the relative intensity of the adsorbate-adsorbent interactions, adsorbate-adsorbate association, the sorption of the supercritical fluid at the solid interface, and the solubility of the sorbate in the critical fluid. As we shall demonstrate, competitive adsorption between the sorbate and the supercritical fluid at the gas-solid interface is a significant mechanism which should be considered in the proper design of adsorption/desorption methods which incorporate dense gases as one of the active phases. 

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