NO Feedback Regulation of NOS

NO has recently been proposed to autoinhibit neuronal NOS (Rogers and Ignarro, 1992). We have investigated whether an NOS heme-NO com- 

Abu-Soud, H. M., and Stuehr, D. J. (1993). NO synthases reveal a role for calmodulin in controlling electron transfer. Proc. Natl. Acad. Sci. U.S.A. 90, 10769-10772. 

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