NMEs, New molecular entities

Figure 2 NMEs and BLAs received by the FDA in the last 10 years show the rapid decrease in new products developed. Abbreviations NME, new molecular entities BLA, biological license application.

Figure 1 CYP-based drug-drug interaction studies decision tree. Source. Adapted from Ref. 7. Abbreviation. NME, new molecular entity.

Fig. 1 New molecular entity withdrawals. NME. new molecular entity Prescription Drug User Free Act years. (From Ref. [6].)...

KEY IND investigational new drug NME - new molecular entity FDA - Food and Drug Administration. SOURCE Office of Technology Assessment, 1993, based on data supplied by FDA (see appendix I). 

NCE-New Chemical Entity (Pharmaceuticals) NME-New Molecular Entity (Biologies) Global 2006 market estimates by author. 

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