Nitrourea with amides

Helf (Ref 6) investigated ten hew materials as flash smoke suppressants in pro pints. Guanylurea Nitrate was the most promising compd with regard to physical chemical props, stability, and 0 balance. Guanylnitro Urea was unsuitable for propints contg NG. Carbohydrazide-N-carboxy amide Carbohy-drazide-N, N -dicarboxyamide showed desirable promise but depended on a special starting material. Ammonium,Nitrourea, Diammonium -methylene-bis-(nitrosohydroxylamine) ... 

An H acidity function scale has been constructed for methoxide ion in methanol and its mixtures with DMSO (10-80%, v/v) using the dissociation of 11 amides (114) as the anchors for the scale.The degradation pathways of the anti-flammatory and analgesic lomoxicam (115), which contains an amide bond, have been examined recently. In acid, cleavage of the amide bond was the main reaction path and in alkaline and neutral solution the proton shift of the enolic hydroxyl initiated the major degradation pathway. The mechanism of hydrolysis of some A-nitrobenzamides (116) in strong acid follow an -1 mechanism with O-protonation but, in more moderate acid, they exhibit a neutral water-catalysed mechanism. /V-Methyl-/V-nitroacetamide (117) shows only the neutral water-catalysed process. Nitrourea follows an, 4-1 acid-catalysed mechanism. ... 

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