2-Nitroso-6-nitrotoluene

Nitro-4-nitrosotoluene, 22, 47 p-Nitrophenol, 20, 60 2-Nitroso-5-nitrotoluene, 22, 44 />-Nitrotoluene, 21, 97... 

A) 2-Nitroso-5-nitrotoluene.—In a 5-1. round-bottomed flask fitted with a mechanical stirrer is placed 50 g. (0.33 mole) of pulverized 5-nitro-2-aminotoluene (Note 1). To this is added an ice-cold solution of 200 cc. of concentrated sulfuric acid in 50 cc. of water. While the suspension is stirred at room temperature, a solution of Caro s acid is prepared, as follows to 175 cc. of ice-cold sulfuric acid (sp. gr. 1.84) in a 2-1. beaker is added 300 g. (1.11 moles) of pulverized potassium persulfate. The mixture is thoroughly stirred with a glass rod, and to it is added 900 g. of crushed ice and 300 cc. of water. 

The filtrates, on standing overnight, deposit 5-5.6 g. of crude 2-nitroso-5-nitrotoluene, which is not included in the weights recorded. It may be added to the product obtained by steam distillation. 

B) 2,5-Dinitrobenzoic Acid.—A suspension of 20 g. (0.12 mole) of the air-dried 2-nitroso-5-nitrotoluene in 100 cc. of water is prepared in a 500-cc. Erlenmeyer flask, and to it is added 50 g. (0.17 mole) of powdered potassium dichromate (Note 5). The flask is placed in an ice-salt bath, and the mixture is stirred vigorously by means of an efficient stirrer. When the temperature has dropped to 5°, 175 cc. of concentrated sulfuric acid is added in a thin stream (Note 6), while the temperature is not allowed to exceed 35°. After all the sulfuric acid has been added the mixture is stirred and heated to 50°. The source of heat is removed, and the temperature is maintained between 50° and 55° by cooling in an ice bath as the exothermic reaction takes place (Note 7). After twenty minutes the temperature is raised to 65° 3°, and held there for one hour longer. 

N-Nitroso-N-methyl-N -nitroguanidine, diazomethane from, 41, 10 Nitrosomethylurethane, warning because a carcinogen, 43, 86 o-Nitrotoluene, condensation with ethyl oxalate, 43,40... 

The complete sequence of reduction products was produced from 2,6-dinitrotoluene by Salmonella typhimurium strain TA 98 (Sayama et al. 1992)—2-nitroso-6-nitrotoluene, 2-hydroxylamino-6-nitrotoluene, and 2-amino-6-nitrotoluene. 

Al-Nitrosodiethanolamine, 2 449, 450 Nitroso dyes, 9 263-264 Nitro soluble dyes, 7 373t Nitroso soluble dyes, 7 373t Nitrosomonas, use in recirculating aquaculture biofiltration, 3 196 P-Nitrostyrenes, preparation by nitration of styrenes, 16 581 Nitrosyl chloride, 20 634 Nitrosyl complexes, osmium, 19 642 Nitrosyl perchlorate, 18 279 Nitrosyl tetrafluoroborate, 4 144t n-Nitrotoluene, 17 263... 

Nitro-2,4,-d methy ozobeBsene red oil, bp ca 215° at 11 mm press prepd from 2-nitroso-3-nitrotoluene and aniline in glacial acetic acid (Ref 3)... 

Nitroso-d-naphthol, II, 61-62 Nitroso- 3-phenylhydroxylamine, IV, 21 w-Nitrotoluene, III, 91-93 -Nitrotoluene, II, 53 iw-Nitro- -toluidine, III, 91 Nitrous anhydride, IV, 27... 

Nitrophenols, alkylation, 148 o-Nitrophenol-p-sulfonic add, 107 p-Nitrophenyloxamic add, 93 o-NitrophenyBiydrazine, 97 p-NitrophenyDiydrazine, 95 Nitrophenylpyrazolones, 97 Nitrosobenzene, 78 p-Nitrosodiediylaniline, 309 p-Nitrosodimediylaniline, 308, 311 reduction, 78, 312 Nitroso- -naphthol, 80, 201 p-Nitrosophenol, 85 Nitrosylsulfuric add, 9, 247 o-Nitrotoluene, 53, 160 m-Nitrotoluene, 51 Nitrotoluenes, 3... 

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