Nitroso-di-N-propylamine

An EPA method was created for measuring NDMA and six additional nitrosamines in drinking water (EPA Method 521) [55]. This method uses GC/ chemical ionization (CI)-MS/MS and enables the measurement of NDMA and six other nitrosamines (N-nitrosomethylethylamine, N-nitrosodiethylamine, N-nitroso-di-n-propylamine, N-nitroso-di- -butylamine, N-nitrosopyrrolidine, and N-nitrosopiperidine) in drinking water at detection limits ranging fi om 1.2 to 2.1 ng/L. A liquid chromatography (LC)/MS/MS method [56] can also be used to measure nine nitrosamines, including N-nitrosodiphenylamine, which is thermally unstable and cannot be measured using the EPA Method. 

FIGURE 7.18 (a) PICI spectrum of V-nitroso-di-n-propylamine (peak 4 in Figure 7.17a) with ammonia as the reagent gas. (b) PICI spectrum of V-nitroso-di-n-propy-lamine (peak 4 in Figure 7.17b) with isobutane as the reagent gas. (c) PICI spectrum of V-nitroso-di-n-propylamine (peak 4 in Figure 7.17c) with methane as the reagent gas. (Masucci and Caldwell, unpublished data.)... 

SVOCs lists four compounds, N-nitroso-di-n-propylamine, hexachlorocyclopen-tadiene, 2,4-dinitrophenol, and 4-nitrophenol. These compounds must show a response factor greater than 0.05. 

N-nitrosamines are a group of compounds characterized by a nitroso group (N=0) attached to the nitrogen of an aromatic or aliphatic secondary amine. N-nitrosodi-N-propylamine is a suspected reaction byproduct from the nitrosation of di-N-propylamine. Two pesticides are suspected to contain some form of nitrosamines. 

Synonym N-nitrosodi-n-propylamine, N-nitroso-N-propyl-1-propanamine Chemical Name di-n-propylnitrosoamine, N-nitrosodi-n-propylamine CAS Registry No 621-64-7... 

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