Nitrogen-catabolite repression

Nitrogen-catabolite repression (NCR) and nitrogen-catabolite inactivation (NCI) two superimposed regulatory mechanisms affecting uptake systems for nitrogenous compounds... 

Nitrogen-catabolite repression of GAPl synthesis has been studied in mutant strains containing mutations such as npil or npi2 which destroy the permease inactivation mechanism. With the help of these mutants, it could be clearly demonstrated that GAPl synthesis is repressed in cells grown in the presence of ammonium ions. 

Subileau, M., Schneider, R., Salmon, J.-M., Degryse, E. (2008) Nitrogen catabolite repression modulates the production of aromatic thiols characteristic of Sauvignon Blanc at the level of precursor transport. FFMS Yeast Research, 8, 771-780. 

Cunningham TS, Andhare R, Cooper TG (2000) Nitrogen catabolite repression of DAL80 expression depends on the relative levels of Gatlp and Ure2p production in Saccharomyces cerevisiae. J Biol Chem 275 14408-14414... 

DAL2 Allantoicase, converts allantoate to urea and ureidoglycolate in the second step of allantoin degradation expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation... 

DAL5 Allantoin permease ureidosuccinate permease expression is constitutive but sensitive to nitrogen catabolite repression... 

Ammonium permease involved in regulation of pseudohyphal growth belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+) expression is under the nitrogen catabolite repression regulation... 

Boczo, E. M., Cooper, T. G., Gedeon, T., Mischaikow, K., Murdock, D. G., Pratrap, S., et al. (2005). Structure theorems and the dynamics of nitrogen catabolite repression in yeast. Proceedings of the National Academy of Sciences of the United States of America, 102, 5647-5652. 

Wiame, J.-M., Grenson, M., Arst, H. N. (1985). Nitrogen catabolite repression in yeasts and filamentous fungi. Advances in Microbial Physiology, 26,1-38. 

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