5- Nitro-orotic acid

OCH3, SH, NH2, CHg, or COOH,205 adenine-thymine base pair171,175,184, 185 and its cationic and anionic forms209 (for the charge densities at C-5 and C-6 positions in uracil, thymine, 5-amino- 5-nitro- and 6-methyl-uracil, 6-azathymine and orotic acid, see refs. 187, 188) it-HMO + a-Del Re calculations on uracil,369,397 5-fluoro- and 5-bromouracil,397 5,6-dihydrouracil and its anionic form369 n-SCF MO + a-Del Re... 

Of 2,4-dialkoxypyrimidines, only 2,4di-tert-butoxy pyrimidine19 and 5-nitro-2,4-dimethoxypyrimidine20 failed to react in the normal Hilbert-Johnson fashion, and anomalous O-2-glycosyl derivatives have been obtained21 with a 2,4-dialkoxypyrimidine substituted in position 6, namely, with 2,4-diethoxy-6-meth3dpyrimidine anomeric 2-tetra-0-acetyl-D-glucopyranosyloxy-4-ethoxy-6-methylpyrimidines (18) resulted. Unsuccessful attempts to synthesize an X-l-ribo-furanosyl derivative of orotic acid (uracil-6 carboxylic acid) have been reported.22... 

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