3 -Nitro-1,8-naphthyridin-2,7 -dione

Wlien more than one oxo (hydroxy) group is present, a mixture of ehloro-hydroxy- and diehloro-naphthyridines is usually formed. Tlius, reflux of 3-nitro-l,8-naphthyridin-2,7(lH,8H)-dione (114) with phosphorus oxy-ehloride gives the three halogeno eompounds (115,116, and 117), the ratio being dependent on the reaetion time (94EJMC735). [Pg.312]

Phenyl-2//-pyrido 2,3-<7 [l,3]oxazine-2,4(l//)-dione (64) with diethyl malo-nate gave ethyl 4-hydroxy-2-oxo-l-phenyl-l,2-dihydro-l,8-naphthyridine-3-carboxylate (65) (reactants, NaH, 150°C 85%) 453,407 the same substrate (64) with ethyl nitroacetate gave 4-hydroxy-3-nitro-l-phenyl-1,8-naphthyr-idin-2(lfl)-one (66) (NaH/MeCONMe2, 100°C 77%).1191... [Pg.193]

Hydroxy-1,6-naphthyridin-5(6Z/)-one 4-Hydroxy-3-nitro-1,6-naphthyridin-2(l//)-one 6-Hydroxy-7-phenyl-1,6-naphthyridin-5(6//)-one 4-Hydroxy-1,6,7-trimethyl-1,6-naphthyridine-2,5(1//,6//)-dione... [Pg.356]

Nitro-l,8-naphthyridine-2,4-diamine 3-Nitro-l,8-naphthyridine-2,5(1//,8//)-dione 3-Nitro-l,8-naphthyridine-2,7(l//,8//)-dione 3-Nitro-l,8-naphthyridin-2(l/Z)-one... [Pg.407]

Nitration of l,8-naphthyridin-2,5(lH,8H)-dione (55a) and some of its derivatives (55b-55d) was studied by Carboni and coworkers (72GCI253). They observed the formation of the 3-nitro derivatives (56a/56b) from (55a/ 55d) under more severe conditions from (55b/55c) the 3,6-dinitro derivatives (57a/55b) are obtained. In the case when a carboxyl group is present, decarboxylation is observed. [Pg.296]

Nitro-l, 8-naphthyridin-2,7(lH,8H)-dione 3-Nitro-l, 8-naphthyridin-2,5(lH,8H)-dione... [Pg.332]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...