Nitriles thioimidate synthesis

Aminohydrazines (640) are useful intermediates for the synthesis of reduced 1,2,4-triazines. With nitriles, carboxylic acids, imidates, thioimidates or orthocarboxylates, they form l,4,5,6-tetrahydro-l,2,4-triazines (641) (78HC(33)189, p. 629), with carbon disulfide they give the 3-thiones (642) <78HC(33)189, p.648), and with aldehydes or ketones hexahydro-1,2,4-triazines (643) are formed <78HC(33)189, p. 657). 

---