Ni-Catalysed C-H Bond Activation

Chemical transformations through transition metal-catalysed C-H bond activation have attracted much attention owing to the remarkable potential for atom economy and environmental sustainability. Among a range of transition-metal catalysts used, nickel in combination with various ligands plays an important role in performing the transformation. 

1 C-H Aiylation, All lation or Alkenylation with Organometallic Reagents 

NiBr2/bpy catalyses cross-coupling of benzoxazoles and 1,3,4-oxadiazoles with aiylhoronic acids using K3PO4 as base and atmospheric air as oxidant, affording 

Electron-deficient heteroaryls are poor substrates in catalytic direct aiylation reactions. However, under Ni(COD)2/PCy3 catalysis a variety of 

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