New Generations of Glycosyl Donors

Details pertaining to the design, preparation, reactivity, and oligosaccharide synthesis technology based on the MOP and TOPCAT leaving groups are discussed in the following four chapters [Chaps. 17-20], 

Schmidt and W. Kinzy, Anomeric oxygen activation for glycoside synthesis—the tri-chloroacetimidate method, Adv. Carbohydr. Chem. Biochem. 50 21 (1994), and references cited therein. 

Hanessian and J. Banoub, Preparation of 1.2 tram glycosides in the presence of silver Inflate, Methods Carbohydr. Chem. 8 247 (1980) (b) S. Hanessian and J. Banoub, Chemistry of the glycosidic linkage. An efficient synthesis of 1,2-rrans-disaccharides, Carbohydr. Res. 5J C13 (1977). 

The Chemical Synthesis of Peptides, Oxford Science Publications, Clarendon Press, Oxord, 1991. 

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In the first part of this review, the basic principles of chemical glycosylation reactions are discussed this way the advantages of 0-glycosyl trichloroacetimidates and related systems as glycosyl donors become obvious. Many new methods for the generation of 0-glycosyl trichloroacetimidates and for their use as glycosyl donors have been introduced which are... 

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