Neurotransmitter receptor sites in the

Although nerve agents exert toxic effects on the CNS and PNS indirectly through AChE inhibition (Koelle, 1975, 1981), nerve agents may also affect nerve impulse transmission by additional mechanisms at NMJs (see reviews by Somani and Husain, 2001 Marrs, 2007 Gupta and Milatovic, 2010) and at neurotransmitter receptor sites in the CNS (Myhrer and Aas, 2010 Weissman and Raveh, 2010). Rao et al. (1987) reported that VX caused an... 

---