Neuromuscular blocking agents for overdose

A decrease in stability is often a desirable modification. For example, succinylcholine (suxamethonium 3.25) — a neuromuscular blocking agent used in surgery — has a self-limiting activity, since the ester is hydrolyzed in about 10 minutes, preventing the potential for overdose, which could be fatal with more stable curarizing agents. 

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