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Neuromuscular Assay system

In a study of the stereochemical preferences for curarimimetic neuromuscular junction blockade, the / ,i -isomer of A -methylpavine methiodide showed a modest statistical superiority in potency in two of the four assay systems employed. ... [Pg.68]

Figure 15.2. Drosophila larval neuromuscular junction system. A wandering third-instar larva is dissected open to reveal the ventral neuromusculature (see Figure 15.1). The peripheral nerve is severed and stimulated with a glass suction electrode. The muscle is recorded from in two-electrode voltage-clamp (TEVC) configuration. The postsynaptic excitatory junctional current (EJC) is recorded to assay synaptic transmission bottom inset). Top inset) Basis of synaptic transmission event being evoked by nerve stimulation and recorded via ion flux through muscle glutamate receptors. Figure 15.2. Drosophila larval neuromuscular junction system. A wandering third-instar larva is dissected open to reveal the ventral neuromusculature (see Figure 15.1). The peripheral nerve is severed and stimulated with a glass suction electrode. The muscle is recorded from in two-electrode voltage-clamp (TEVC) configuration. The postsynaptic excitatory junctional current (EJC) is recorded to assay synaptic transmission bottom inset). Top inset) Basis of synaptic transmission event being evoked by nerve stimulation and recorded via ion flux through muscle glutamate receptors.
See other pages where Neuromuscular Assay system is mentioned: [Pg.92]    [Pg.321]    [Pg.4]    [Pg.150]    [Pg.59]    [Pg.327]    [Pg.108]    [Pg.220]    [Pg.151]   
See also in sourсe #XX -- [ Pg.197 ]



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