Near-field scanning microwave microscopy

Near-field scanning microwave microscopy Oligonucleotide DNA and RNA — (42)... 

Near-field scanning microwave microscopy (NSMM) is another system that has been used for label-free detection of both DNA and RNA molecules (42). NSMM monitors the microwave reflectance, a factor that depends on the dielectric permittivity profile across the microarray surface (42). This parameter is, in turn, dependent on the length and surface coverage of the strands, as well as on the hybridization state of the molecules (e.g., unhybridized single-stranded probe vs. hybridized duplex). NSMM technique demonstrated an acceptable resolution (potentially less than 50 pm) and comparable sensitivity to the fluorescent detection (42). 

SNMM Scanning near-field microwave microscopy... 

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