Nasal mucosal erythema

Reviews A review of antiresorptive therapies for osteoporosis identified the following as the most commonly reported adverse effects of calcitonin therapy irritation of the nasal passage nasal mucosal erythema and minor bleeding sneezing rhinitis and nausea [3 ]. Across studies these side effects generally occurred in less than 10% of patients receiving calcitonin treatment. 

The presence of acute inflammatory manifestations (i.e., erythema nodosum, polyarthritis, and fever), termed Lofgren s syndrome, portends an excellent prognosis, with high rates (>85%) of SRs (9,14,33,37,38). Conversely, the following factors were associated with a worse prognosis in sarcoidosis age onset >40 years (9,36), hypercalcemia (9), extrathoracic disease (9,20), lupus pernio (9), splenomegaly (36), pulmonary infiltrates on chest radiograph (9,36), chronic uveitis, cystic bone lesions, nasal mucosal sarcoidosis (9), and lower annual family income (14). 

In 15 patients who underwent autologous stem-cell transplantation and who received sickle cell disease, oral and intestinal mucositis were significantly less severe [16 ]. Adverse reactions that were attributable to the drug included erythema, mild rashes, pruritus, nasal congestion, and low-grade fever. All the compfications were easily manageable and resolved after completion of treatment. 

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