Narco tine

Papaveraceae Papaver somniferum Morphine Codeine Thebaine Papaverine Narco tine Narceine Isoboldine... 

The biological properties of narco tine have been reviewed (1). The antitussive activity of narcotine once more was a subject of many papers (259-271) and the question of this property, when compared with that of codeine, still remains unclear. Codeine is said to be superior in this respect to narcotine (272) but, according to other authors (273, 274), narcotine has some advantage over codeine. The antitussive activity of different stereoisomers of narcotine have also been studied (271). Narcotine-V-oxide showed an increased antitussive activity (271, 275, 276) and narcotine resinate was recommended as a long-acting antitussive (277, 278), as were the esters of 6-hydroxymethylnarcotine (279). The phar-... 

The treatment of 3,4-dehydro-9-hydroxylaudanosine (18) with 2% acetic acid on the steam bath yields veratric aldehyde and hydroxylaudanosine, whereas the treatment of narco tine diol (19 R = OMe) and hydrastine diol (19 R = H) with acetic acid and tin(ii) chloride yields the reduced anhydro-compounds (20 R = OMe and H). The oxidation of narcotine with mercury(n) acetate and EDTA affords tarconine methyl ether (21), meconine, and opianic acid. ... 

Phospuomolvddic acid forms a precipitate which is bright yellow, with aniliue, morphine, veratrine, aconitine, emetine, atropine, byoscyamine, theine, theobromine, couhne, and nicotine brownish-yellow with narco-tine, codeine, and pij erine yeUowish-white with quinine, cinchonine and strychnine yolk-yellow with brucine. 

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