2-Naphthylacetic acid, preparation from

The reaction with sulfur and morpholine can be applied to the preparation of aromatic acids containing polynuclear residues. Methyl 2-naph-thyl ketone refluxed for 16 h with a 50% excess of sulfur and morpholine furnishes a 90% yield of the thiomorpholide of 2-naphthylacetic acid, from which 2-naphthylacetic acid is obtained by refluxing for 5 h with aqueous sulfuric and acetic acid (yield 90%). 1-Acenaphthylacetic acid is prepared by heating 1-acetylacenaphthene with sulfur and ammonium sulfide at... 

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