2- naphthyl 4-phenoxyphenyl

At biphenyl, naphthyl, 3,4-dichlorophenyl, 4-nitraphenyl 3-phenoxyphenyl, 2-benzothiophenyl, 4-phenoxathiinyl R - CHj, C2H5... 

Similarly prepared were 4-phenoxyphenyl phenyl tellurium, and 4-ethoxyphenyl 1-naphthyl tellurium. 

A range of 2-aryl 3-substituted pyridine atropoisomers were obtained in 75-90% yields (aryl = phenyl, 2-methoxyphenyl, 2-phenoxyphenyl and 1-naphthyl) by orT/io-directed metallation with LDA (lithium diisopropylamide) - substitution (with RCOR or MeaSiCl), followed by reaction of the... 

R,ipo = phenyl, phenoxyphenyl, benzylphenyl,naphthyl, tetrahydronaphthyl, indanyl,... 

This last tyj of nonsteroidal anti-inflammatory drugs, such as ibuprofen ([rac-2-(4-iso-butylphenyl) propionic acid], 5), flurbiprofen ([rac-2-((3-fluoro-4-phenyl)phenyl)propionic acid], 6), fenoprofen ([rac-2-(3-phenoxyphenyl)propionic acid], 7), suprofen ([rac-2-(4(2-fliienyloxo)phenyl)propionic acid, 8], carprofen ([rac-2-(6-chloro-9H-cabazolyl) propionic acid], 9), naproxen ([5(+)-2-(6-methoxy-2-naphthyl)propionic acid], 10), Dexketoprofen ([S(+)-2-(3-benzoylphenyl)propionic acid], 11), flunoxaprofen ([S(+)-2-(2(4-fluoro-phenyl)benzoxazol-5-yl)propionic acid], 12), or ketorolac ([5(+)-5-benzoyl-2,3-dihidro-1/i-pyrrolizine-l-carboxylic acid], 13, thromethamine salt marketed as Toradol), have a more promising future. 

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