N-tiered architecture

N-Tier Architecture (multitier architecture) is a software architecture model where multiple software components serve different purposes and are physically separated, such as client-server architectures. 

Middleware architecture is the replacement of Client/Server architecture. The Middleware is defined as 3-tier (or N-tier), while the traditional Client/Server is defined as 2-tier architecture. In this paper, we will highlight and focus on the Middleware concept rather than the 3-tier arehiteeture. 

Approximately six years after Denkewalter s patent, two new architectures were published in 1985. Newkome et al. 41 relied on triester amidation with tris for the construction of polyols (8) possessing maximal 1 — 3 C-based branching. Repetition of the sequence was precluded by surface steric inhibition towards nucleophilic substitution. Tomalia et al. 42a reported the preparation of an entire series of dendrimers (9, up to the 7th tier) possessing trigonal, l—>2 N- based, branching centers. To date, availability has... 

---