N-Phenylsuccinimide

CX = O or NCgH3-Me2-2,6 cocatalyst Et2AlCl. The cis content of the polymer varies from 41 to 100% depending on the nature of the chelating diolate ligand. Norborn-2-ene-5-spiro-3/-eA o-succinic anhydride, and norborn-2-ene-5-spiro-3/-exu-N-phenylsuccinimide and derivatives. 

Another interesting case is shown in the scheme below for the phototransformation of (E)-2-benzylidene-3-isopropylldene-N-phenylsuccinimide (9 Ar=Ph). This compound changes rapidly from pale yellow to orange-red dien irradiated in benzene on prolonged... 

If one takes the contribution of a hydrogen to activity as 0.0, then one can calculate the group contribution for a derivative by simply subtracting the activity of the parent from the activity of that derivative. For example, for the series of N-phenylsuccinimides reported by Takayama and Fujinami, we would find that the 3-Cl contribution was... 

C. Takayama and A. Fujinami, Pestic. Biochem. Physiol. 12,163 (1979). Quantitative Structure-Activity Relationships of Antifungal N-Phenylsuccinimides and N-Phenyl-1,2-dimethylcyclopropanedicarboximides. 

Therapeutic Function Anticonvulsant Chemical Name l-Methyl-3-phenyl-2,5-pyrrolidinedione Common Name N-Methyl-a-phenylsuccinimide Structural Formula ... 

Barbiturates (mephobarbital, hexobarbital, pentobarbital, l-methyl-5-(2-propyl)-5-(n-propyl)barbituric acid, 5-ethyl-1 -methyl-5-(n-propyl) barbituric acid), benzoin, a-methyl-a-phenylsuccinimide, gluthethimide, methylthiohy-dantoin-proline, methyl mandelate... 

Phensuximide. t-Methyt-3-phenyt-2,5-pyrroti-dinedione S-tnethyl-2-phinylsuccitiirnide JV-methyl-a-phenylsuccinimide Lifene Succitimal Milontin Miron tin. CmHmNC mol wt 189.21. C 69.82%, H 5.86%, N 7.40%, O 16.91%. rrepd by the action of methylamine on phenylsuc-cinic acid Miller, Long, J. Am, Chem. Soc. 73, 4895 (1951) U.S, pat. 2,643,258 <1953 to Parke, Davis). 

N-Methyl-2-phenylsuccinimide 2,5-Pyrrolidinedione, 1-methyl-3-phenyl Fensuximid B.C.P. 1973,U.S.P. 

N, 2-Dimethyl-2-phenylsuccinimide 2, 5-Pyrrolidinedione, 1,3-dimethyl-3-phenyl-, U.S.P., Celontin (Parke-Davis)... 

N-Me [86-34-0]. l-Methyl-3 phenyl-2,5-pyrrolidinedione, 9CL N Methyl-l-phenylsuccinimide. Phensuximide BAN, INN. Epimid. Lepsol. Lifene. Milontin. Milonton. Mirontin. Petimid. Succitimal. PM 334. Fensuximide C H N02 M 189.213 Anticonvulsant. Fine cryst. (EtOH). Mp 71-73°. 

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