N-phenylbenzohydroxamic acid

In an apparatus set up for steam distillation and containing a rapidly stirred solution of 5.0 gm (0.023 mole) of jV-benzoylphenylhydroxylamine (N-phenylbenzohydroxamic acid) in 100 ml of a 1 1 solution of ethanol-acetic acid, cooled to —20°C, is added 11.5 gm (0.024 mole based on 94% purity) of lead tetraacetate in one portion. After approximately 10 sec (when the initial green color just begins to darken), 100 ml of water is added and the brown or black mixture is rapidly subjected to steam distillation. The distillate is collected in a receiver filled with chopped ice. The product is isolated by filtration of the distillate. Finally, it is dried by pressing dry between filter papers to yield 1.4-2.0 gm (56-80%), m.p. 66°-68°C. 

C13H11N02 N-phenylbenzohydroxamic acid 304-88-1 504.40 44.307 2 25853 C13H13N 3-methyl-N-phenyl aniline 1205-64-7 589.15 52.512 1.2... 

Hydroxylamine derivatives are used in determination of certain metals [112,113]. For example, the substitution of a benzoyl group (CeHsCO) for one of hydrogen atoms in hydroxylamine gives benzohydroxamic acid. Other important reagents in this group are N-benzoyl-N-phenylhydroxylamine (BPHA), also called N-phenylbenzohydroxamic acid [114,115] and N-furoylphenylhydroxylamine. All these reagents form extractable chelates and are used for determination of metals, e.g., V(V), Mn, Ti, Fe(III), and Nb. 

N-(4-Methylphenyl)nonanohydroxamic acid (C H2y02N) N-(4-Methylphenyl)tetradecanohydroxamic acid ( 21 35 2 N-Phenyl-2-furohydroxamic acid (C H OgN) N-Phenyl-2-thienohydroxamic acid (C H 02NS) 4 Methyl-N-phenylbenzohydroxamic acid (C H g02N)... 

N-Phenyl-3-trifluoromethylbenzohydroxamic acid N-Phenyl-4-trifluoromethylbenzohydroxamic acid (C H q02NF ) 5-Nitro-N phenyl-3-trifluoromethylbenzohydroxamic acid (C H O N2F2) 4-Carboxy-N-phenylbenzohydroxamic acid ethyl ester 4-Methoxy-N-phenylbenzohydroxamic acid... 

The kinetics and mechanism of alkaline hydrolysis of Af-tolylbenzohydroxamic acids (90 X = H, Me, Cl) in aqueous dioxane have been reported. A study of the effect of solvents on the mechanism of the acid hydrolysis of N-phenylbenzohydroxamic acid (91) has revealed that methanol and dioxane have a rate-enhancing effect, but DMF, acetone, EtOH, and propan-2-ol exert a rate-decreasing effect. The alkaline hydrolysis in aqueous dioxane of N-p-tolylcinnamohydroxamic acid (92) proceeds via initial rate-limiting formation of a tetrahedral intermediate. ... 

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