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N-Oxidation of quinoxalines

Various peracids have been used for the N-oxidation of quinoxalines, but the most convenient reagent for many 2-substituted and 2,3-disub-stituted quinoxalines is 30% aqueous hydrogen peroxide in acetic acid. With this reagent, oxidation has been carried out at temperatures ranging from 20° to 90°.108-112 For example, 2-methyl-3-phenylquin-oxaline (91) when treated with peroxide and acetic acid at 56° for 14 hours yields a mixture of the 1-oxide (92) and the 1,4-dioxide (93).112... [Pg.390]

See other pages where N-Oxidation of quinoxalines is mentioned: [Pg.392]    [Pg.392]    [Pg.28]   
See also in sourсe #XX -- [ Pg.22 ]



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