N-Benzoyl-a-

Anhydro-acylation of l,2-dihydro-2-oxo-l-pyridylacetic acid with acid anhydrides yields bicyclic meso-ionic 4-acyl-l,3-oxazol-5-ones (67). Huisgen and his co-workers have reported extensive studies of the monocyclic meso-ionic l,3-oxazol-5-ones (66), which they have lightheartedly named munchnones. Cyclodehydration of N-benzoyl-A -methyl-C-phenylglycine using acetic anhydride at 55° gives the 3-methyl-2,4-diphenyl derivative (66, R = = Ph R = Me) as... 

Benzoyl-aminosauren1 z. B. N-Benzoyl-a-(l-methyl-allyl)-alanin (78%) aus N-Benzo-yl-alanin-(tra s-2-butenylester)1 2. 

Die Substitution des Brom-Atoms in N-Benzoyl-a-brom-glycin-methylester ist auch unter Radikalbedingungen moglich4,5. Die Reaktion mit 2-funktionalisierten Allylstannanen in Gegenwart von Azo-bis-isobutyronitril (AIBN) fiihrt zu Derivaten von y,<5-ungesat-tigten a-Amino-carbonsauren ... 

This process proceeds as a DKR [13, 190] because the DMAP catalyst promotes not only the asymmetric alcoholysis of the azlactone but also its racemization under the reaction conditions the N-benzoyl a-amino acid ester product does not racemize under these conditions. Johannsen has also screened chiral DMAP 21 (Fig. 8.4) for this transformation, but obtained poorer yields and selectivities [102],... 

Glycin N-Benzoyl-a-chlor- -butyl-ester E14a/3, 292 (OH - Cl)... 

Organophosphorus extractants such as di(2-ethyl-hexyl) phosphoric acid (DEHPA), 2-ethylhexyl-phosphonic acid mono-2-ethylhexyl ester (EHPA), N-benzoyl-A-phenylhydroxylamine (BPHA), and tetra-octylethylenediamine (TOEDA) are often used due to their solubility properties in the stationary organic phase [1-3]. 

Standard vanadium solution 1 mg/ml. Preparation as in Section 55.2.1. N-Benzoyl-A-phenylhydroxylamine (BPHA), 0.1% solution in CHCI3. 

Most experimental studies have supported the nondissociative mechanism (a) for this reaction,but one study reported the following results the polyphos-phoric acid (PPA)-catalyzed Beckmann rearrangement of pinacolone oxime produced N-f-butylacetamide, while the PPA-catalyzed rearrangement of 2-methyl-2-phenylpropiophenone oxime produced N-benzoyl-a, -dimethyl-benzylamine and benzamide. Carrying out the rearrangement on a mixture of pinacolone oxime and 2-methyl-2-phenylpropiophenone oxime produced the products expected from each reactant, plus Af-f-butylbenzamide and N-acetyl-a,a-dimethylbenzylamine. 

Meyer zu Reckendorf, W. et al., Chem. Ber., 1972,105, 2546 synth, a-D-pyr isopropylidene N-benzoyl, a-D-fur isopropylidene N-benzoyl, (x-D-fur-isopropylidene N-Ac)... 

Ga. 2 N NaOH added during 40 min. at 2-4° to a suspension of N-benzoyl-a-chloro-f-caprolactam in methanol-water, stirred 1 hr. at 0-3°, treated with more base, and stirred an additional 3 hrs. at 0-3° -benzamido-a-chloro-caproic acid. Y 94.5%. R. Tull et al., J. Org. Ghem. 29, 2425 (1964). 

Bimethylamino-benzyl]-benzoat 13 I 231. 4-Methoxy-N-benzoyl-a- phenatityjaraia 13 1 234, 23.5. 

N-Benzoyl-a-cyanobenzyl-3,4-diethoxyphenethylamine heated 1 hr. with 85%-phosphoric acid on a steam bath a- (3,4-diethoxyphenethylamino) phenylacetic acid. Y 92%. Limitation s. J. Gardent, G. r. 256, 3140 (1963). 

Correction to Em values due to IR drop should be made. > N-Benzoyl-A-phenyl hydroxylamine. 

Nakai, H., Sato, Y., Mizoguchi, T., and Kanaoka, Y., Preparation of N-benzoylamines by photodecarboxylation of N-benzoyl-a-amino acids, Synthesis, 141,1982. 

Carbohydrate derivatives. Alcohol-free ether satd. with water added to a soln. of l-bromo-3,4,6-tribenzoyl-N-benzoyl-a-D-glucosamine in chloroform, and the product allowed to crystallize 1,3,4,6-tetrabenzoyl-a-D-glucosamine hydro-bromide. Y 73%. F. Micheel and H. Kochling, B. 92, 2832 (1959) s. a. H. Weid-mann and H. K. Zimmerman, Jr., B. 92, 2828 (1959). 

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