Myoglobin reaction with peroxides

B. Reaction of Myoglobin with Hydrogen Peroxide Lipoxygenase Activity... 

Matsui T, Ozaki S, Liong E, Phillips GN, Watanabe Y (1999) Effects of the location of distal histidine in the reaction of myoglobin with hydrogen peroxide. J Biol Chem 274 2838-2844... 

Fig. 4.5. ESR spectrum of the ferryl myoglobin radical (Turner et al., 1990). ESR spectrum observed on reaction of (a) metmyoglobin (225 //M) and (b) oxymyoglobin with 250 / M hydrogen peroxide in the presence of 25 mM DMPO at pH 7.4 under normoxic...

In the editorial preface to the first volume of Advances in Catalysis the decision was made known not to publish reviews of specialized topics in biocatalysis but from time to time to bring reports in which the relationship and parallelism between this special field and normal catalysis are discussed. This is the first of these reports. Its purpose is to examine the reactions of four hemoproteins, hemoglobin, myoglobin, peroxidase, and catalase, which all contain the same coordination compound of iron—ferrous or ferric protoporphyrin attached to different protein molecules, with oxygen, hydrogen peroxide, and in a few cases additional reducing substances. Some of these reactions are specific ... 

Hemoglobin and myoglobin in their ferric forms show rudimentary peroxidatic and catalatic activity, but ferrous peroxidase does not combine reversibly with molecular oxygen. Ionic iron also gives the hydrogen peroxide reactions but not the combination with oxygen. 

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